A framework for assessing 16S rRNA marker-gene survey data analysis methods using mixtures.
نویسندگان
چکیده
منابع مشابه
Assessing and improving methods used in operational taxonomic unit-based approaches for 16S rRNA gene sequence analysis.
In spite of technical advances that have provided increases in orders of magnitude in sequencing coverage, microbial ecologists still grapple with how to interpret the genetic diversity represented by the 16S rRNA gene. Two widely used approaches put sequences into bins based on either their similarity to reference sequences (i.e., phylotyping) or their similarity to other sequences in the comm...
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1Murdoch Childrens Research Institute, The Royal Children’s Hospital, Flemington Rd, Parkville, Victoria 3052 Australia 2 Monash University, Victoria 3800, Australia 3The University of Melbourne, Victoria 3050, Australia 4Victorian Life Sciences Computation Initiative, The University of Melbourne, Parkville Campus, LAB-14, 700 Swanston St, Carlton, Victoria 3053, Australia 5The Royal Women’s Ho...
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ژورنال
عنوان ژورنال: Microbiome
سال: 2020
ISSN: 2049-2618
DOI: 10.1186/s40168-020-00812-1